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Synthesis and Antiribosomal Activities of 4′- O -, 6′- O -, 4″- O -, 4′,6′- O - and 4″,6″- O -Derivatives in the Kanamycin Series Indicate Differing Target Selectivity Patterns between the 4,5- and 4,6-Series of Disubstituted 2-Deoxystreptamine Aminoglycoside Antibiotics
Kato, Takayuki, Yang, Guanyu, Teo, Youjin, Juskeviciene, Reda, Perez-Fernandez, Déborah, Shinde, Harish M., Salian, Sumanth, Bernet, Bruno, Vasella, Andrea, Böttger, Erik C., Crich, DavidLanguage:
english
Journal:
ACS Infectious Diseases
DOI:
10.1021/acsinfecdis.5b00069
Date:
August, 2015
File:
PDF, 959 KB
english, 2015