P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice
Tang, Seng Chuan, Kort, Anita, Cheung, Ka Lei, Rosing, Hilde, Fukami, Tatsuki, Durmus, Selvi, Wagenaar, Els, Hendrikx, Jeroen J. M. A., Nakajima, Miki, van Vlijmen, Bart J. M., Beijnen, Jos H., SchinkLanguage:
english
Journal:
Molecular Pharmaceutics
DOI:
10.1021/acs.molpharmaceut.5b00470
Date:
September, 2015
File:
PDF, 1.77 MB
english, 2015