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1,4-Oxazine β-secretase (BACE1) inhibitors: from hit generation to orally bioavailable brain penetrant leads.
Rombouts, Frederik J.R., Tresadern, Gary, Delgado, Óscar, Martinez Lamenca, Carolina, Van Gool, Michiel, García-Molina, Aránzazu, Alonso De Diego, Sergio A., Oehlrich, Daniel, Prokopcova, Hana, AlonsoLanguage:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.5b01101
Date:
September, 2015
File:
PDF, 4.42 MB
english, 2015