Verification of the major metabolic oxidation path for the...

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  • Verification of the major metabolic oxidation path for the...

Verification of the major metabolic oxidation path for the naphthoyl group in chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2) antagonist 2-(2-(1-naphthoyl)-8-fluoro-3,4-dihydro-1 H -pyrido[4,3- b ]indol-5(2 H )-yl)acetic acid (Setipiprant/ACT-129968)

Risch, Philippe, Pfeifer, Thomas, Segrestaa, Jerome, Fretz, Heinz, Pothier, Julien
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Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.5b00824
Date:
September, 2015
File:
PDF, 2.20 MB
english, 2015
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