Discovery of...

Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2 H )-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases

Ruggeri, Roger B., Buckbinder, Leonard, Bagley, Scott W., Carpino, Philip A., Conn, Edward L., Dowling, Matthew S., Fernando, Dilinie P., Jiao, Wenhua, Kung, Daniel W., Orr, Suvi T. M., Qi, Yingmei, R
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Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.5b00963
Date:
October, 2015
File:
PDF, 1.64 MB
english, 2015
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