4-(( R )-2-{[6-(( S )-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y 12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel
Caroff, Eva, Hubler, Francis, Meyer, Emmanuel, Renneberg, Dorte, Gnerre, Carmela, Treiber, Alexander, Rey, Markus, Hess, Patrick, Steiner, Beat, Hilpert, Kurt, Riederer, Markus A.Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.5b00933
Date:
November, 2015
File:
PDF, 1.60 MB
english, 2015