Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis.
Onishi, C., Mori-Kimachi, S., Hirade, T., Abe, M., Taketani, T., Suzumiya, J., Sugimoto, T., Yamaguchi, S., Kapur, R., Fukuda, S.Volume:
290
Language:
english
Journal:
Journal of Biological Chemistry
DOI:
10.1074/jbc.A114.568287
Date:
November, 2015
File:
PDF, 498 KB
english, 2015