Metabolism and Disposition of Oral Dabrafenib in Cancer...

Drug Metabolism and Disposition 2013 / 12 Vol. 41; Iss. 12

Metabolism and Disposition of Oral Dabrafenib in Cancer Patients: Proposed Participation of Aryl Nitrogen in Carbon-Carbon Bond Cleavage via Decarboxylation following Enzymatic Oxidation

Bershas, D. A., Ouellet, D., Mamaril-Fishman, D. B., Nebot, N., Carson, S. W., Blackman, S. C., Morrison, R. A., Adams, J. L., Jurusik, K. E., Knecht, D. M., Gorycki, P. D., Richards-Peterson, L. E.
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Volume:
41
Language:
english
Journal:
Drug Metabolism and Disposition
DOI:
10.1124/dmd.113.053785
Date:
December, 2013
File:
PDF, 1.11 MB
english, 2013
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