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The nutrient and energy sensor Sirt1 regulates the hypothalamic-pituitary-adrenal (HPA) axis by altering the production of the prohormone convertase 2 (PC2) essential in the maturation of corticotropin releasing hormone (CRH) from its prohormone in male rats
Toorie, Anika M., Cyr, Nicole E., Steger, Jennifer S., Beckman, Ross, Farah, George, Nillni, Eduardo A.Language:
english
Journal:
Journal of Biological Chemistry
DOI:
10.1074/jbc.M115.675264
Date:
January, 2016
File:
PDF, 3.38 MB
english, 2016