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Increasing the Binding Affinity of VEGFR-2 Inhibitors by Extending their Hydrophobic Interaction with the Active Site: Design, Synthesis and Biological Evaluation of 1-Substituted-4-(4-methoxybenzyl)phthalazine Derivatives
Eldehna, Wagdy M., Abou-Seri, Sahar M., El Kerdawy, Ahmed M., Ayyad, Rezk R., Hamdy, Abdallah M., Ghabbour, Hazem A., Ali, Mamdouh M., Abou El Ella, Dalal A.Language:
english
Journal:
European Journal of Medicinal Chemistry
DOI:
10.1016/j.ejmech.2016.02.029
Date:
February, 2016
File:
PDF, 1.87 MB
english, 2016