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In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-κB and activation of caspase-8.
Gentle, Ian E., Wong, W. Wei-Lynn, Evans, Joseph M., Bankovacki, Alexandra, Cook, Wendy D., Khan, Nufail R., Nachbur, Ulrich, Rickard, James, Anderton, Holly, Moulin, Maryline, Lluis, Josep Maria, MouVolume:
291
Language:
english
Journal:
Journal of Biological Chemistry
DOI:
10.1074/jbc.A110.216226
Date:
January, 2016
File:
PDF, 542 KB
english, 2016