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Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3 H -imidazo[4,5- b ]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhibitor
Lapierre, Jean-Marc, Eathiraj, Sudharshan, Vensel, David, Liu, Yanbin, Bull, Cathy O, Cornell-Kennon, Susan, Iimura, Shin, Kelleher, Eugene W., Kizer, Darin E., Koerner, Steffi, Makhija, Sapna, MatsudLanguage:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.6b00619
Date:
June, 2016
File:
PDF, 924 KB
english, 2016