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Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase.
Huber, B. E., Austin, E. A., Richards, C. A., Davis, S. T., Good, S. S.Volume:
91
Language:
english
Journal:
Proceedings of the National Academy of Sciences
DOI:
10.1073/pnas.91.17.8302
Date:
August, 1994
File:
PDF, 1000 KB
english, 1994