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Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor
Wootten, Denise, Reynolds, Christopher A., Smith, Kevin J., Mobarec, Juan C, Furness, Sebastian G.B., Miller, Laurence J., Christopoulos, Arthur, Sexton, Patrick M.Language:
english
Journal:
Biochemical Pharmacology
DOI:
10.1016/j.bcp.2016.08.015
Date:
August, 2016
File:
PDF, 1.51 MB
english, 2016