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Consequences of molecular recognition in the S 1 -S 2 intersubsite region of papain for catalytic-site chemistry. Change in pH-dependence characteristics and generation of an inverse solvent kinetic isotope effect by introduction of a P 1 -P 2 amide bond into a two-protonic-state reactivity probe
Brocklehurst, K, Kowlessur, D, Patel, G, Templeton, W, Quigley, K, Thomas, E W, Wharton, C W, Willenbrock, F, Szawelski, R JVolume:
250
Language:
english
Journal:
Biochemical Journal
DOI:
10.1042/bj2500761
Date:
March, 1988
File:
PDF, 2.26 MB
english, 1988