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CD8+ but not CD4+ T cells require cognate interactions with target tissues to mediate GVHD across only minor H antigens, whereas both CD4+ and CD8+ T cells require direct leukemic contact to mediate GVL
Matte-Martone, C., Liu, J., Jain, D., McNiff, J., Shlomchik, W. D.Volume:
111
Language:
english
Journal:
Blood
DOI:
10.1182/blood-2007-11-125294
Date:
April, 2008
File:
PDF, 4.06 MB
english, 2008