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An in silico PBPK-PD coupled approach to assess zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration
Small, Ben G, Jamei, Masoud, Rostami-Hodjegan, Amin, Polak, SebastianVolume:
81
Language:
english
Journal:
Journal of Pharmacological and Toxicological Methods
DOI:
10.1016/j.vascn.2016.02.082
Date:
September, 2016
File:
PDF, 72 KB
english, 2016