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Discovery of (1 S ,2 R ,3 S ,4 S ,5 R ,6 R )-2-amino-3-[(3,4- difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid hydrochloride (LY3020371.HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity
Chappell, Mark D., Li, Renhua, Smith, Stephon C., Dressman, Bruce A, Tromiczak, Eric G., Tripp, Allie E., Blanco, Maria-Jesus, Vetman, Tatiana, Quimby, Steven J., Matt, James, Britton, Thomas C., FivuLanguage:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.6b01119
Date:
November, 2016
File:
PDF, 1.39 MB
english, 2016