Four-week sub-acute toxicity study of S-(-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido-(1,2,3,-de)(1,4) benzoxazine-6-carboxylic acid hemihydrate (DR-3355) in CD rats and cynomolgus monkeys.

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