Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum antifungal activity.
Hargrove, Tatiana Y., Garvey, Edward P., Hoekstra, William J., Yates, Christopher M., Wawrzak, Zdzislaw, Rachakonda, Girish, Villalta, Fernando, Lepesheva, Galina. I.Language:
english
Journal:
Antimicrobial Agents and Chemotherapy
DOI:
10.1128/aac.00570-17
Date:
May, 2017
File:
PDF, 1.12 MB
english, 2017