Design and Discovery of...

Design and Discovery of N-(2-methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A potent, selective and efficacious RAF inhibitor targeting RAS mutant cancers

Nishiguchi, Gisele A., Rico, Alice, Tanner, Huw R., Aversa, Robert J., Taft, Benjamin Robert, Subramanian, Sharadha, Setti, Lina, Burger, Matthew T, Wan, Lifeng, Tamez, Victoriano N. A., Smith, Aaron,
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Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.6b01862
Date:
May, 2017
File:
PDF, 1.50 MB
english, 2017
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