Lead optimization generates CYP11B1 inhibitors of...

Journal of Medicinal Chemistry 2017 / 06

Lead optimization generates CYP11B1 inhibitors of pyridylmethyl isoxazole type with improved pharmacological profile for the treatment of Cushing’s disease

Emmerich, Juliette, van Koppen, Chris J, Burkhart, Jens L., Hu, Qingzhong, Siebenbürger, Lorenz, Boerger, Carsten, Scheuer, Claudia, Laschke, Mathias W., Menger, Michael D., Hartmann, Rolf W.
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Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.7b00437
Date:
June, 2017
File:
PDF, 1.16 MB
english, 2017
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