Introduction of 2- O -benzyl abasic nucleosides to the 3′-overhang regions of siRNAs greatly improves nuclease resistance
Nagaya, Yuki, Kitamura, Yoshiaki, Shibata, Aya, Ikeda, Masato, Akao, Yukihiro, Kitade, YukioLanguage:
english
Journal:
Bioorganic & Medicinal Chemistry Letters
DOI:
10.1016/j.bmcl.2017.10.070
Date:
October, 2017
File:
PDF, 879 KB
english, 2017