Human genetic variation alters CRISPR-Cas9 on- and...

Proceedings of the National Academy of Sciences 2017 / 12

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci

Lessard, Samuel, Francioli, Laurent, Alfoldi, Jessica, Tardif, Jean-Claude, Ellinor, Patrick T., MacArthur, Daniel G., Lettre, Guillaume, Orkin, Stuart H., Canver, Matthew C.
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Language:
english
Journal:
Proceedings of the National Academy of Sciences
DOI:
10.1073/pnas.1714640114
Date:
December, 2017
File:
PDF, 1.21 MB
english, 2017
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