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Identification and Mitigation of Reactive Metabolites of 2-Aminoimidazole-Containing Microsomal Prostaglandin E Synthase-1 Inhibitors Terminated due to Clinical Drug-Induced Liver Injury
Norman, Bryan H., Fisher, Matthew J, Schiffler, Matthew A., Kuklish, Steven L., Hughes, Norman E., Czeskis, Boris A, Cassidy, Kenneth C, Abraham, Trent L, Alberts, Jeffrey J, Luffer-Atlas, DebraLanguage:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.7b01806
Date:
February, 2018
File:
PDF, 1.35 MB
english, 2018