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GRL-079, a novel P2-Tp-THF-C5-alkylamine- and P2’ -Abt-containing HIV-1 protease inhibitor, is extremely potent against multi-drug-resistant HIV-1 variants including HIV DRVRp51 and has a high genetic barrier against the emergence of resistant variants
Delino, Nicole S., Aoki, Manabu, Hayashi, Hironori, Hattori, Shin-ichiro, Chang, Simon B., Takamatsu, Yuki, Martyr, Cuthbert D., Das, Debananda, Ghosh, Arun K., Mitsuya, HiroakiLanguage:
english
Journal:
Antimicrobial Agents and Chemotherapy
DOI:
10.1128/AAC.02060-17
Date:
February, 2018
File:
PDF, 2.25 MB
english, 2018