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Exploiting the inherent photophysical properties of the major tirapazamine metabolite in the development of profluorescent substrates for enzymes that catalyze the bioreductive activation of hypoxia-selective anticancer prodrugs
Shen, Xiulong, Laber, Charles H., Sarkar, Ujjal, Gallazzi, Fabio, Johnson, Kevin M, Mahieu, Nathaniel Guy, Hillebrand, Roman, Fuchs-Knotts, Tarra, Barnes, Charles L., Baker, Gary A., Gates, Kent S.Language:
english
Journal:
The Journal of Organic Chemistry
DOI:
10.1021/acs.joc.7b03035
Date:
February, 2018
File:
PDF, 969 KB
english, 2018