The reason for the low Ca 2+ -sensitivity of thin filaments...

Biochemical and Biophysical Research Communications 2018 / 07 Vol. 502; Iss. 2

The reason for the low Ca 2+ -sensitivity of thin filaments associated with the Glu41Lys mutation in the TPM2 gene is “freezing” of tropomyosin near the outer domain of actin and inhibition of actin monomer switching off during the ATPase cycle

Avrova, Stanislava V., Karpicheva, Olga E., Rysev, Nikita A., Simonyan, Armen O., Sirenko, Vladimir V., Redwood, Charles S., Borovikov, Yurii S.
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Volume:
502
Language:
english
Journal:
Biochemical and Biophysical Research Communications
DOI:
10.1016/j.bbrc.2018.05.145
Date:
July, 2018
File:
PDF, 612 KB
english, 2018
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