PBPK Model of Morphine Incorporating Developmental Changes in Hepatic OCT1 and UGT2B7 Proteins to Explain the Variability in Clearances in Neonates and Small Infants
Emoto, Chie, Johnson, Trevor N., Neuhoff, Sibylle, Hahn, David, Vinks, Alexander A., Fukuda, TsuyoshiLanguage:
english
Journal:
CPT: Pharmacometrics & Systems Pharmacology
DOI:
10.1002/psp4.12306
Date:
June, 2018
File:
PDF, 2.99 MB
english, 2018