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Physiologically based pharmacokinetic model (PBPK) of itraconazole and two of its metabolites to improve the predictions and the mechanistic understanding of CYP3A4 drug-drug interactions
Prieto Garcia, Luna, Janzen, David, Kanebratt, Kajsa P., Ericsson, Hans, Lennernas, Hans, Lundahl, AnnaLanguage:
english
Journal:
Drug Metabolism and Disposition
DOI:
10.1124/dmd.118.081364
Date:
August, 2018
File:
PDF, 5.56 MB
english, 2018