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Use of physiologically-based pharmacokinetic (PBPK) modeling to evaluate the effect of chronic kidney disease on the disposition of hepatic CYP2C8 and OATP1B drug substrates
Tan, Ming-Liang, Zhao, Ping, Zhang, Lei, Ho, Yunn-Fang, Varma, Manthena V S, Neuhoff, Sibylle, Nolin, Thomas D, Galetin, Aleksandra, Huang, Shiew-MeiLanguage:
english
Journal:
Clinical Pharmacology & Therapeutics
DOI:
10.1002/cpt.1205
Date:
August, 2018
File:
PDF, 1.24 MB
english, 2018