Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification
Vaidyanathan, Sriram, Azizian, Krist T., Haque, A.K.M. Ashiqul, Henderson, Jordana M., Hendel, Ayal, Shore, Sabrina, Antony, Justin S., Hogrefe, Richard I., Kormann, Michael S.D., Porteus, Matthew H.,Volume:
12
Language:
english
Journal:
Molecular Therapy - Nucleic Acids
DOI:
10.1016/j.omtn.2018.06.010
Date:
September, 2018
File:
PDF, 1.62 MB
english, 2018