A highly bioactive Lys-deficient IFN leads to a...

ACS Synthetic Biology 2018 / 10

A highly bioactive Lys-deficient IFN leads to a site-specific di-PEGylated IFN with equivalent bioactivity to that of unmodified IFN-α2b

Imada, Takashi, Moriya, Koji, Uchiyama, Masahiko, Inukai, Naoto, Hitotsuyanagi, Mitsuhiro, Masuda, Akiko, Suzuki, Takehiro, Ayukawa, Shotaro, Tagawa, Yoh-ichi, Dohmae, Naoshi, Kohara, Michinori, Yamam
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Language:
english
Journal:
ACS Synthetic Biology
DOI:
10.1021/acssynbio.8b00188
Date:
October, 2018
File:
PDF, 1.23 MB
english, 2018
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