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Enhance 4′-epidaunorubicin production of engineering Streptomyces coeruleorubidus strains via both knockout of daunorubicin-consuming enzymes dnrX and dnrU , and multiple copies of rate-limiting enzyme aveBIV
Shao, Lei, Chen, Ji-Ye, Zi, Jia-Chen, Chen, Dai-JieLanguage:
english
Journal:
Journal of Chemical Technology & Biotechnology
DOI:
10.1002/jctb.5741
Date:
July, 2018
File:
PDF, 432 KB
english, 2018