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5-Substituted-N-pyridazinylbenzamides as Potent and Selective LRRK2 Inhibitors: Improved Brain Unbound Fraction Enables Efficacy
Ding, Xiao, Stasi, Luigi Piero, Dai, Xuedong, Long, Kai, Peng, Cheng, Zhao, Baowei, Wang, Hailong, Sun, Changhui, Hu, Huan, Wan, Zehong, Jandu, Karamjit S., Philps, Oliver J., Chen, Yan, Wang, Lizhen,Language:
english
Journal:
Bioorganic & Medicinal Chemistry Letters
DOI:
10.1016/j.bmcl.2018.11.054
Date:
November, 2018
File:
PDF, 544 KB
english, 2018