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Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the anti-diabetic PPARγ drug pioglitazone
Mosure, Sarah, Shang, Jinsai, Eberhardt, Jerome, Brust, Richard, Zheng, Jie, Griffin, Patrick R., Forli, Stefano, Kojetin, Douglas J.Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.8b01573
Date:
January, 2019
File:
PDF, 2.47 MB
2019