Identification of on-target mutagenesis during correction...

APL Bioengineering 2018 / 12 Vol. 2; Iss. 4

Identification of on-target mutagenesis during correction of a beta-thalassemia splice mutation in iPS cells with optimised CRISPR/Cas9-double nickase reveals potential safety concerns

Alateeq, Suad, Ovchinnikov, Dmitry, Tracey, Timothy, Whitworth, Deanne, Al-Rubaish, Abdullah, Al-Ali, Amein, Wolvetang, Ernst
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Volume:
2
Journal:
APL Bioengineering
DOI:
10.1063/1.5048625
Date:
December, 2018
File:
PDF, 1.35 MB
2018
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