The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K
Mons, Elma, Jansen, Ineke D. C., Loboda, Jure, van Doodewaerd, Bjorn R., Hermans, Jill, Verdoes, Martijn, van Boeckel, Constant A. A., van Veelen, Peter A., Turk, Boris, Turk, Dusan, Ovaa, HuibLanguage:
english
Journal:
Journal of the American Chemical Society
DOI:
10.1021/jacs.8b11027
Date:
January, 2019
File:
PDF, 2.94 MB
english, 2019