Chemical modification of PS-ASO therapeutics reduces...

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Nature Biotechnology 2019 / 4

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index

Shen, Wen, De Hoyos, Cheryl L., Migawa, Michael T., Vickers, Timothy A., Sun, Hong, Low, Audrey, Bell, Thomas A., Rahdar, Meghdad, Mukhopadhyay, Swagatam, Hart, Christopher E., Bell, Melanie, Riney, S
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Language:
english
Journal:
Nature Biotechnology
DOI:
10.1038/s41587-019-0106-2
Date:
April, 2019
File:
PDF, 3.33 MB
english, 2019
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