11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
Gent, Rachelle, du Toit, Therina, Swart, Amanda C.Journal:
The Journal of Steroid Biochemistry and Molecular Biology
DOI:
10.1016/j.jsbmb.2019.04.018
Date:
April, 2019
File:
PDF, 536 KB
2019