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Identification and CRISPR/Cas9 Knockout of the Endogenous C1s Protease in CHO Cells Eliminates Aberrant Proteolysis of Recombinantly Expressed Proteins
Li, Sophia, Yu, Bin, Byrne, Gabriel, Wright, Meredith, O'Rourke, Sara, Mesa, Kathryn, Berman, Phillip W.Journal:
Biotechnology and Bioengineering
DOI:
10.1002/bit.27016
Date:
May, 2019
File:
PDF, 1.19 MB
2019