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Inverting Small Molecule-Protein Recognition by the Fluorine Gauche Effect: Selectivity Regulated by Multiple H → F Bioisosterism
Bentler, Patrick, Bergander, Klaus, Daniliuc, Constantin G., Mück-Lichtenfeld, Christian, Jumde, Ravindra P., Hirsch, Anna K. H., Gilmour, RyanLanguage:
english
Journal:
Angewandte Chemie International Edition
DOI:
10.1002/anie.201905452
Date:
June, 2019
File:
PDF, 1.71 MB
english, 2019