Leveraging atropisomerism to obtain a selective inhibitor...

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ACS Chemical Biology 2019 / 08

Leveraging atropisomerism to obtain a selective inhibitor of RET kinase with secondary activities towards EGFR mutants.

Toenjes, Sean T., Garcia, Valeria, Maddox, Sean M, Dawson, Gregory A., Ortiz, Maria A., Piedrafita, F. Javier, Gustafson, Jeffrey L.
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Language:
english
Journal:
ACS Chemical Biology
DOI:
10.1021/acschembio.9b00407
Date:
August, 2019
File:
PDF, 1.07 MB
english, 2019
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