Profile of a Highly Selective Quaternized Pyrrolidine Betaine α v β 6 Integrin Inhibitor—(3 S )-3-(3-(3,5-Dimethyl-1 H -pyrazol-1-yl)phenyl)-4-((1 S and 1 R ,3 R )-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective Methylation
Barrett, Tim N., Taylor, Jonathan A., Barker, Daniel, Procopiou, Panayiotis A., Thompson, James D. F., Barrett, John, Le, Joelle, Lynn, Sean M., Pogany, Peter, Pratley, Cassie, Pritchard, John M., RopJournal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.9b00819
Date:
August, 2019
File:
PDF, 3.02 MB
2019
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