Tumors with TSC mutations are sensitive to CDK7 inhibition...

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Journal of Experimental Medicine 2019 / 09

Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion

Zarei, Mahsa, Du, Heng, Nassar, Amin H., Yan, Rachel E., Giannikou, Krinio, Johnson, Sneha H., Lam, Hilaire C., Henske, Elizabeth P., Wang, Yubao, Zhang, Tinghu, Asara, John, Kwiatkowski, David J.
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Language:
english
Journal:
The Journal of Experimental Medicine
DOI:
10.1084/jem.20190251
Date:
September, 2019
File:
PDF, 4.35 MB
english, 2019
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