The Discovery of AM-6494: A Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in vivo Selectivity over BACE2
Pettus, Liping H., Bourbeau, Matthew Paul, Bradley, Jodi, Bartberger, Michael D., Chen, Kui, Hickman, Dean, Johnson, Michael, Liu, Qingyian, Manning, James R., Nanez, Adrian, Siegmund, Aaron, wen, PauLanguage:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.9b01034
Date:
October, 2019
File:
PDF, 942 KB
english, 2019