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Discovery of amide-bridged pyrrolo[2,3-d]pyrimidines as tumor targeted classical antifolates with selective uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesis
Xiang, Weiguo, Dekhne, Aamod, Doshi, Arpit, O'Connor, Carrie, Hou, Zhanjun, Matherly, Larry H., Gangjee, AleemLanguage:
english
Journal:
Bioorganic & Medicinal Chemistry
DOI:
10.1016/j.bmc.2019.115125
Date:
October, 2019
File:
PDF, 2.02 MB
english, 2019