501POncogenic mutations at the dimer interface of EGFR lead...

Annals of Oncology 2019 / 10 Vol. 30; Iss. Supplement

501POncogenic mutations at the dimer interface of EGFR lead to formation of covalent homo-dimers and allosteric activation of the kinase domain: A mechanism which alters the selectivity profile of oncogenic EGFR

Buck, E, O’Connor, M, Flohr, A, Iacone, R, Nicolaides, T, Zhang, J, Mayweg, A V, Epstein, D M
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Volume:
30
Journal:
Annals of Oncology
DOI:
10.1093/annonc/mdz244.063
Date:
October, 2019
File:
PDF, 76 KB
2019
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