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Multikilogram synthesis of a potent dual Bcl-2 / Bcl-xL antagonist. Part I. Manufacture of the acid moiety and development of some key reactions
HARDOUIN, Christophe, Baillard, Sandrine, Barière, François, Copin, Chloé, Craquelin, Anthony, Janvier, Solenn, lemaitre, Sylvain, Le Roux, Stéphane, Russo, Olivier, Samson, SébastienLanguage:
english
Journal:
Organic Process Research & Development
DOI:
10.1021/acs.oprd.9b00364
Date:
November, 2019
File:
PDF, 674 KB
english, 2019