P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554)
Li, Wenlong, Sparidans, Rolf, El-lari, Mujtaba, Wang, Yaogeng, Lebre, Maria C., Beijnen, Jos H., Schinkel, Alfred H.Language:
english
Journal:
International Journal of Pharmaceutics
DOI:
10.1016/j.ijpharm.2019.118842
Date:
November, 2019
File:
PDF, 1.45 MB
english, 2019
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